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Framingham Heart Study - Omni 2 Cohort (FHS Omni 2)
Framingham Heart Study - Omni 2 Cohort logo
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Sample details

The FHS began in 1948 and aims to identify common factors or characteristics that contribute to cardiovascular disease. The FHS has since been expanded to become a multigenerational study and to include diverse populations so that risk factors in these different groups can be understood. The FHS Omni 2 was established in order to expand the Omni 1 cohort, an ethnically diverse sample from Framingham, Massachusetts, United States of America. Participants were individuals, both related and unrelated to the Omni 1 cohort, between the ages of 20 and 80 years. Over 400 participants completed baseline assessment from 2003 to 2005 and have since completed further exams from 2009 to 2011 and from 2016 to 2019.

Study design
Cohort

Number of participants at first data collection

410 (participants)

Age at first data collection

20 - 80 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Adults
African-American populations
Asian
First Nations Peoples
Hispanic/Latino populations
Dataset details

Country

United States of America

Year of first data collection

2003

Primary Institutions

Boston University (BU)

Links

framinghamheartstudy.org/participants/participant-cohorts/

nhlbi.nih.gov/science/framingham-heart-study-fhs

doi.org/10.1038/s41569-019-0202-5

Profile paper DOI

doi.org/10.1093/ije/dyv337

Funders

National Heart, Lung, and Blood Institute (NHLBI)

National Institutes of Health (NIH)

Ongoing?
Yes

Data types collected

neuroImagingData
mentalHealthData
dataLinkage
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
  • Interview – phone
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
  • Self-report questionnaire – online
  • Self-report questionnaire – paper or computer assisted
Qualitative data collection
  • None
Neuroimaging data collection
  • Diffusion Tensor Imaging (DTI)
  • Magnetic Resonance Imaging (MRI)
Linked or secondary data
  • Healthcare data
Features

Engagement

  • Participant or community advisory groups
  • Community engagement
  • Keywords

    Alzheimer's disease (AD)
    Biological samples/biospecimens
    Cardiovascular health and disease
    Dementia
    Ethnic minorities
    Genetics
    Neuroimaging

    Consortia and dataset groups

    Framingham Heart Study
    Global Alzheimer’s Association Interactive Network (GAAIN)
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