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GESTation and Environment (GESTE)
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Sample details

The initial aim of GESTE was to investigate the association between maternal blood polybrominated diphenyl ether (PBDE) concentrations measured in early pregnancy and serum thyroid hormone levels assessed at less than 20 weeks of pregnancy, at delivery, and in cord blood. The study was later expanded to follow the children of the pregnant women. The study recruited 800 women from a hospital in Quebec, Canada, between 2007 and 2008. Around half were recruited before 20 weeks of pregnancy, and the rest were enrolled at delivery. Children of the women have been assessed at age 2 years, 6 to 7 years and 8 to 12 years.

Study design
Cohort, Cohort - birth, Cohort - primary caregiver and child, Biobank

Number of participants at first data collection

800 (mother-child dyads)

Age at first data collection

≥ 18 years (mothers)

Birth (children)

Participant year of birth

Varied (mothers)

2008 - 2009 (children)

Participant sex
All

Representative sample at baseline?
No

Sample features

Children
Mother and child dyad
Newborns, infants and babies
Pregnant people
Dataset details

Country

Canada

Year of first data collection

2007

Primary Institutions

University of Sherbrooke (Université de Sherbrooke, UdeS)

Links

maelstrom-research.org/study/geste

doi.org/10.1093/aje/kwt141

doi.org/10.1289/EHP9674

doi.org/10.1186/s12940-016-0134-z

Funders

Canadian Institutes of Health Research (CIHR, Instituts de recherche en santé du Canada, IRSC)

Fonds de Recherche du Québec - Santé (FRQS)

National Institutes of Health (NIH)

Ongoing?
Yes

Data types collected

mentalHealthData
dataLinkage
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
  • Interview – phone
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
Qualitative data collection
  • None
Neuroimaging data collection
  • None
Linked or secondary data
  • Healthcare data
Features

Engagement

  • None
  • Keywords

    Biological samples/biospecimens
    Biomarkers
    Cognition
    Environmental factors
    Human development
    Infant biosamples
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