The initial aim of GESTE was to investigate the association between maternal blood polybrominated diphenyl ether (PBDE) concentrations measured in early pregnancy and serum thyroid hormone levels assessed at less than 20 weeks of pregnancy, at delivery, and in cord blood. The study was later expanded to follow the children of the pregnant women. The study recruited 800 women from a hospital in Quebec, Canada, between 2007 and 2008. Around half were recruited before 20 weeks of pregnancy, and the rest were enrolled at delivery. Children of the women have been assessed at age 2 years, 6 to 7 years and 8 to 12 years.
Study design
Cohort, Cohort - birth, Cohort - primary caregiver and child, Biobank
Number of participants at first data collection
800 (mother-child dyads)
Age at first data collection
≥ 18 years (mothers)
Birth (children)
Participant year of birth
Varied (mothers)
2008 - 2009 (children)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2007
Primary Institutions
University of Sherbrooke (Université de Sherbrooke, UdeS)
Profile paper DOI
Funders
Canadian Institutes of Health Research (CIHR, Instituts de recherche en santé du Canada, IRSC)
Fonds de Recherche du Québec - Santé (FRQS)
National Institutes of Health (NIH)
Ongoing?
Yes
Data types collected
Engagement
Keywords