German Infant Study on the Influence of Nutrition Intervention plus Air pollution and Genetics on Allergy Development (GINIplus)

Sample details

GINIplus is a prospective population-based birth cohort study. Healthy, mature newborns with German parents were recruited from obstetric hospitals between September 1, 1995 and October 31, 1997 in Munich or until June 30, 1998 in Wesel. The aim of the GINIplus study was initially to investigate whether early childhood nutrition can influence the development of allergic diseases and also to observe the natural course of atopic diseases. As the children became older, other research topics were added (e.g., mental well-being, lung function, nutrition, weight, and physical activity). Participants were followed-up since birth at 1, 2, 3, 4, 6, 10, 15, 20, and at 25 years of age, as well as during the COVID-19 pandemic.

Study design
Cohort - birth

Number of participants at first data collection

5,991 (participants)

Age at first data collection

Birth (participants)

Participant year of birth

1995 - 1998 (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Newborns, infants and babies

Dataset details

Country

Germany

Year of first data collection

1995

Primary Institutions

Evangelical Hospital Düsseldorf (Evangelisches Krankenhaus Düsseldorf)

Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)

Leibniz Research Institute for Environmental Medicine (Leibniz-Institut für umweltmedizinische Forschung, IUF)

Ludwig Maximilian University of Munich (Ludwig-Maximilians-Universität München, LMU)

Marien-Hospital Wesel

Links

ginistudie.de/

helmholtz-munich.de/en/epi/cohort/giniplus

Profile paper DOI

doi.org/10.5414/alx01455e

Funders

European Commission Seventh Framework Programme

Heinrich Heine University Düsseldorf (Heinrich-Heine-Universität Düsseldorf, HHU)

Helmholtz Zentrum München – German Research Center for Environmental Health (Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt, GmbH)

Leibniz Research Institute for Environmental Medicine (Leibniz-Institut für umweltmedizinische Forschung, IUF)

Ludwig Maximilian University of Munich (Ludwig-Maximilians-Universität München, LMU)

Ongoing?
Yes

Data types collected