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Genetic Links to Anxiety and Depression Study (GLAD)
Genetic Links to Anxiety and Depression Study logo
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Sample details

The GLAD study is a large-scale study of the genetic and environmental risk factors of anxiety and depression. Recruitment initially targeted individuals over the age of 16 years living in England, and having had a prior or current experience of clinical anxiety or depression (a formal diagnosis is not necessary), with online recruitment via a broad media campaign and the study website. The study has since opened to individuals in Wales, Scotland, and Northern Ireland, and since April 2024, is also recruiting participants with no history of anxiety and/or depression.

Study design
Biobank, Cohort - research programme

Number of participants at first data collection

35,324 (participants)

Recruitment is ongoing

Age at first data collection

16 years ≥ (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Adults
Dataset details
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Countries

England, Northern Ireland, Scotland, United Kingdom of Great Britain and Northern Ireland, Wales

Year of first data collection

2018

Primary Institutions

King's College London (KCL)

Links

gladstudy.org.uk/

cataloguementalhealth.ac.uk//

Funders

National Institute for Health and Care Research (NIHR)

Ongoing?
Yes

Data types collected

mentalHealthData
dataLinkage
Quantitative data collection
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
  • Self-report questionnaire – online
Qualitative data collection
  • None
Neuroimaging data collection
  • None
Linked or secondary data
  • Healthcare data
Features

Engagement

  • Community engagement
  • Keywords

    Anxiety
    Biological samples/biospecimens
    Depression
    Environmental factors
    Genetic factors
    Risk factors

    Consortia and dataset groups

    Catalogue of Mental Health Measures
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