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Gothenburg MCI study
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The Gothenburg mild cognitive impairment (MCI) study, launched in 1999, is a single-center clinical-pathophysiologic study investigating early and manifest phases of Alzheimer’s disease (AD) and vascular dementia (VaD). Patients are referred to the memory clinic at the Sahlgrenska University Hospital in Mölndal, Sweden. Patients are aged between 50 and 79 years, have a mini mental state examination (MMSE) result above 18, present with self- or informant-reported cognitive decline, and have a duration of cognitive decline of 6 months or more. All participants are examined at baseline and after 2, 4, 6, and 10 years.

Study design
Cohort - clinical

Number of participants at first data collection

664 (participants)

115 (controls)

Age at first data collection

50 - 79 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
A population of memory clinic patients between 1999 and 2013.

Sample features

Patients and clinical populations
Dataset details

Country

Sweden

Year of first data collection

1999

Primary Institutions

University of Gothenburg (Göteborgs universitet)

Links

gu.se/en/research/kognitiv-medicin

Funders

Adlerbert Research Foundation

Alzheimer’s Association

Gothenburg Medical Society (Göteborgs Läkaresällskap)

Gun and Bertil Stohne's Foundation (Gun och Bertil Stohnes stiftelse)

Inga Britt & Arne Lundberg Research Foundation

Ongoing?
Yes

Data types collected

neuroImagingData
mentalHealthData
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
Qualitative data collection
  • None
Neuroimaging data collection
  • Electroencephalography (EEG)
  • Magnetic Resonance Imaging (MRI)
  • Single-photon emission computed tomography (SPECT)
Linked or secondary data
  • None
Features

Engagement

  • None
  • Keywords

    Alzheimer's disease (AD)
    Biomarkers
    Brain injury or damage
    Cardiovascular health and disease
    Cognitive assessments
    Dementia
    Mild cognitive impairment (MCI)
    Neuropsychological testing
    Pathophysiology
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