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General Population Cohort (GPC)
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Sample details

GPC monitors the health demographic dynamics of a rural population in Uganda. Participants are residents of all ages and sexes from the Kyamulibwa sub-county in the Kalungu district. Since its inception, the study has continued to enrol participants, growing from 8,000 to over 15,000 participants in 3,700 households in 2011 and 22,000 in 2024, to better capture the evolving demographic and health trends. The cohort is followed up annually through comprehensive surveys to monitor changes and gather new data.

Study design
Cohort - open

Number of participants at first data collection

22,000 (participants as of 2024)

Recruitment is ongoing

Age at first data collection

Varied (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Economically disadvantaged people
Population-based sample
Rural populations
Villages
Dataset details

Country

Uganda

Year of first data collection

1989

Primary Institutions

London School of Hygiene and Tropical Medicine (LSHTM)

Medical Research Council/Uganda Virus Research Institute and London School of Hygiene & Tropical Medicine Uganda Research Unit (MRC/UVRI

Links

lshtm.ac.uk/research/centres-projects-groups/general-population-cohort

observer.ug/index.php/news/headlines/81975-kyamulibwa-station-a-resilient-public-health-research-hub

Profile paper DOI

doi.org/10.1093/ije/dys234

Funders

Medical Research Council (MRC)

Uganda Virus Research Institute (UVRI)

Wellcome Trust

Ongoing?
Yes

Data types collected

dataLinkage
Quantitative data collection
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
  • Self-report questionnaire – online
  • Self-report questionnaire – paper or computer assisted
Qualitative data collection
  • None
Neuroimaging data collection
  • None
Linked or secondary data
  • Geographic, spatial & environmental data
  • Healthcare data
Features

Engagement

  • Participant or community advisory groups
  • Community engagement
  • Keywords

    Acquired immunodeficiency syndrome (AIDS)
    Antiretroviral therapy (ART)
    Biological samples/biospecimens
    Demographics
    Health and demographic surveillance site (HDSS)
    Human immunodeficiency virus (HIV)
    Infectious disease
    Migration
    Morbidity and mortality
    Noncommunicable diseases

    Consortia and dataset groups

    ALPHA network
    Collaboration for the Establishment of an African Population Cohorts Consortium (CE-APCC)
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