Guangdong Registry of Congenital Heart Disease (GRCHD)
The GRCHD aims to monitor and investigate the incidence, risk factors, and environmental determinants of congenital heart defects (CHDs) across Southern China. As of 2020, the registry includes approximately 14,900 singleton infants - both CHD cases and controls - along with their mothers. Participants were recruited from hospitals in 21 cities across Guangdong Province, China, during inpatient or outpatient visits. All newborns were examined by specialists before hospital discharge or within 72 hours of birth, and each was followed for one year.
Study design
Registry
Number of participants at first data collection
14,929 (mothers)
14,929 (babies)
Recruitment is ongoing
Age at first data collection
Varied (mothers)
Birth (babies)
Participant year of birth
Varied (mothers)
Varied (babies)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2004
Primary Institutions
Guangdong Academy of Medical Sciences (广东省医学科学院)
Guangdong General Hospital (广东省人民医院)
Guangdong Provincial Cardiovascular Institute (GCI)
Profile paper DOI
Funders
Ministry of Science and Technology (中华人民共和国科学技术部)
National Natural Science Foundation of China (国家自然科学基金委员会, NSFC)
Ongoing?
Yes
Data types collected
- Interview – face-to-face
- Physical environment assessment (e.g. pollution, mould)
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Secondary data
- Self-completed questionnaire – paper or computer assisted
- None
- None
- Geographic, spatial & environmental data
- Healthcare data
Engagement
Keywords
