Gubbio Study
The Gubbio Study is a prospective investigation ongoing since 1983 in the city of Gubbio, a medieval hill town in the northern central part of Italy. Original objectives of the study were the control of hypertension and the role of cellular electrolyte handling in hypertension. Other objectives were added during the 30-year activity of the study. The original target cohort consists of individuals aged 5 years and over residing within the medieval walls of the city. To complete family genealogies, individuals residing outside the city were also included. Three active screenings (exams) were conducted. A total of 5,376 individuals participated in Exam 1: 3,537 residents within the city and 1,839 residents outside the city.
Study design
Cohort
Number of participants at first data collection
5,376 (participants)
Age at first data collection
≥ 5 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
1983
Primary Institutions
Northwestern University (NU)
Second University of Naples (Seconda Università degli Studi di Napoli, SUN)
University of Naples Federico II (Università degli Studi di Napoli Federico II)
Links
No website available
Profile paper DOI
Funders
Merck & Co., Inc.
Ministero Italiano di Università e Ricerca
National Heart, Lung, and Blood Institute (NHLBI)
Ongoing?
Yes
Data types collected
- Interview – face-to-face
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Secondary data
- None
- None
- Healthcare data
- Mortality data
Engagement
Keywords
