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Growing Up in Singapore Towards healthy Outcomes (GUSTO)
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Sample details

GUSTO is a prospective, parent-offspring, birth cohort study following around 1,000 Singaporean children and their parents. 1,247 pregnant women aged 18 years and above, in their first trimester, were recruited from two major public maternity units in Singapore between 2009 and 2010. Expectant mothers were Singapore citizens or permanent residents, and of Chinese, Malay, or Indian ethnicity. Mothers receiving chemotherapy, psychotropic drugs or who had type I diabetes were excluded, and parents with mixed ethnic backgrounds were also excluded. 1,176 babies were born between 2009 and 2011, and have since been followed up regularly, along with their parents.

Study design
Cohort - birth, Cohort - primary caregiver and child

Number of participants at first data collection

1,176 (children)

1,247 (mothers)

Age at first data collection

Birth (children)

18 - 46 years (mothers)

Participant year of birth

2009 - 2011 (children)

Varied (mothers)

Participant sex
All

Representative sample at baseline?
No

Sample features

Mother and child dyad
Newborns, infants and babies
Parents
Dataset details

Country

Singapore

Year of first data collection

2009

Primary Institutions

National University of Singapore (NUS)

Links

gustodatavault.sg/about/gusto

gusto.sg/

classic.clinicaltrials.gov/ct2/show/study/NCT01174875

Profile paper DOI

doi.org/10.1093/ije/dyt125

Funders

National Medical Research Council (NMRC)

National Research Foundation (NRF)

Singapore Institute for Clinical Sciences (SICS)

Ongoing?
Yes

Data types collected

neuroImagingData
mentalHealthData
dataLinkage
Quantitative data collection
  • Activity log (e.g. food, sleep, exercise)
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
  • Physical environment assessment (e.g. pollution, mould)
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Wearable devices
Qualitative data collection
  • None
Neuroimaging data collection
  • Diffusion Tensor Imaging (DTI)
  • Electroencephalography (EEG)
  • Functional magnetic resonance imaging (fMRI)
  • Magnetic Resonance Imaging (MRI)
Linked or secondary data
  • Geographic, spatial & environmental data
  • Healthcare data
Features

Engagement

  • Community engagement
  • Keywords

    Allergies
    Anthropometry
    Biological samples/biospecimens
    Epigenetics
    Gene-environment interactions (GxE)
    Genetic predisposition
    Human development
    Maternal morbidity
    Microbiome
    Neurodevelopment
    Neuroimaging
    Physical health
    Postnatal depression
    Prenatal risk factors

    Consortia and dataset groups

    Birth Cohort Consortium of Asia (BiCCA)
    GUSTO Data Vault
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