Hepatitis B Research Network Adult Cohort Study (HBRN Cohort A)
The Hepatitis B Research Network (HBRN) was a multicentre network to investigate the aetiology and progression of the disease and to test the safety and efficacy of current treatment approaches. The primary aims of the HBRN Cohort A Study were to describe participants with hepatitis B virus (HBV) infection and identify predictors of disease activation and progression. Over 1,700 adults who were hepatitis B surface antigen (HBsAg) positive completed baseline assessment at 20 clinical sites across the United States of America and one in Ontario, Canada, beginning in 2011. Participants were followed up after 12 weeks, 24 weeks and every 24 weeks thereafter for up to 288 weeks.
Study design
Cohort, Cohort - clinical
Number of participants at first data collection
1,771 (participants)
Age at first data collection
≥ 18 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Countries
Year of first data collection
2011
Primary Institutions
University of Pittsburgh
Profile paper DOI
Funders
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institutes of Health (NIH)
Ongoing?
No
Data types collected
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Self-report questionnaire – unspecified
- None
- None
- None
Engagement
Keywords
