Lifespan Human Connectome Project Aging (HCP-A)
The HCP-A Study aims to understand how individual experiences influence brain connectivity and how these connections (the “connectome”) change across healthy adulthood. Participants are healthy adults aged 36 to 100+ years, recruited from four states in the United States of America (Washington, Minnesota, Massachusetts, and California) starting in 2017. A subset of participants are completing a follow-up assessment 20–24 months after baseline. As of 2021, data has been collected from 725 participants, with the goal of recruiting over 1,500 participants.
Study design
Cohort
Number of participants at first data collection
725 (participants, as of 2021)
Recruitment is ongoing
Age at first data collection
≥ 36 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
The gender, race and ethnicity, and socio-economic status of people aged 36 and above in the United States of America.
Sample features
Country
Year of first data collection
2017
Primary Institutions
Harvard University
Massachusetts General Hospital (MGH)
University of California, Los Angeles (UCLA)
University of Minnesota
University of Oxford
Profile paper DOI
Funders
National Institutes of Health (NIH)
University of Massachusetts (UMASS)
Washington University in St. Louis
Ongoing?
Yes
Data types collected
- Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
- Interview – phone
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Self-report questionnaire – paper or computer assisted
- None
- Arterial Spin Labelling (ASL)
- Functional magnetic resonance imaging (fMRI)
- Magnetic Resonance Imaging (MRI)
- None
Engagement
Keywords
Consortia and dataset groups
