Health Technology Assessment of Diagnostic Approaches in Alzheimer's Disease
This study aimed to assess the clinical and economic value of techniques for diagnosing Alzheimer's disease and related disorders. Participants were individuals suspected of having a primary neurodegenerative disease who had attended one of four academic memory clinics in the Netherlands (Leiden University Medical Centre, Maastricht University Medical Centre, Radboud University Nijmegen Medical Centre, and VU University Medical Centre). A total of 304 participants were registered in the study at baseline, and data was collected at least 4 times over 24 months.
Study design
Cohort - clinical
Number of participants at first data collection
304 (participants)
Age at first data collection
≥ 18 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2009
Primary Institutions
Erasmus University Rotterdam (Erasmus Universiteit Rotterdam)
Maastricht University (Universiteit Maastricht, UM)
Radboud University Nijmegen (Radboud Universiteit)
VU University Medical Center (VU Medisch Centrum, VUmc)
Profile paper DOI
bmcneurol.biomedcentral.com/articles/10.1186/1471-2377-12-72
Funders
Maastricht University
Ongoing?
No
Data types collected
- Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
- Interview – face-to-face
- Interview – phone
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Self-report questionnaire – paper or computer assisted
- None
- Diffusion Tensor Imaging (DTI)
- Magnetic Resonance Imaging (MRI)
- Positron Emission Tomography (PET)
- None
Engagement
Keywords
