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Healthy Brain Study (HBS)
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Sample details

The HBS is an interdisciplinary study based on multidimensional, dynamic assessments in both the laboratory and the real world. Between 2019 and 2024, the study tested over 900 individuals in their thirties, who have collectively spent over 500,000 hours on tests and tasks. The sample consists of 30 - 39-year-olds living in Nijmegen (Netherlands) and its surroundings. A reasonable level of reading, speaking, and understanding of Dutch (B1 level) was required, implying that the HBS participants do not fully represent the Nijmegen population at large because the illiterate, people with low literacy, or non-Dutch speaking individuals are excluded. As of December 2021, participants performed 755 total lab visits: 380 participants carried out the first assessment, 237 participants the second assessment, and 138 participants the third assessment, completing the entire study protocol.

Study design
Cohort

Number of participants at first data collection

158 (participants)

Age at first data collection

30 - 39 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Middle-aged people
Millennials
Young adults
Dataset details

Country

Netherlands

Year of first data collection

2019

Primary Institutions

Max Planck Institute for Psycholinguistics (Max Planck Instituut voor Psycholinguïstiek)

Radboud University Medical Center (Radboudumc)

Radboud University Nijmegen (Radboud Universiteit)

Links

healthybrainstudy.nl/en/home

osf.io/fr3bq

Funders

Radboud University Nijmegen

Reinier Post Foundation

Ongoing?
No

Data types collected

neuroImagingData
mentalHealthData
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Self-report questionnaire – online
  • Wearable devices
Qualitative data collection
  • None
Neuroimaging data collection
  • Diffusion Tensor Imaging (DTI)
  • Functional magnetic resonance imaging (fMRI)
  • Magnetic Resonance Imaging (MRI)
Linked or secondary data
  • None
Features

Engagement

  • Patients, service users, lived experience involvement
  • Participant or community advisory groups
  • Community engagement
  • Keywords

    Behaviour
    Biological samples/biospecimens
    Brain functioning
    Cognition
    Health and wellbeing
    Health behaviour
    Neuroimaging
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