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Health and Early Microbiota (HELMi)
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Sample details

HELMi is a birth cohort that aims to identify environmental, lifestyle and genetic factors that modify the intestinal microbiota development in the first years of life and their relation to child health and well-being. The cohort consists of 1,055 healthy-term infants born between 2016 and 2018, mainly in the capital region of Finland, and their parents. Participants were followed from birth to 24 months through weekly to monthly questionnaires and repeating microbiota sampling. Home dust samples were collected when the children were between 1.5 and 3 years old. In 2021, a follow-up began to assess participants at ages 4 to 5 years, with plans for additional follow-ups every 4 to 5 years for over 15 years.

Study design
Cohort - birth

Number of participants at first data collection

1,055 (families)

Age at first data collection

Birth (participants)

Participant year of birth

2016 - 2018 (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Children and young people
Healthy
Newborns, infants and babies
Parents
Dataset details

Country

Finland

Year of first data collection

2016

Primary Institutions

University of Helsinki (Helsingin yliopisto)

Links

helmitutkimus.com/

helsinki.fi/en/researchgroups/microbes-inside/finnish-health-and-early-life-microbiota-helmi

ncbi.nlm.nih.gov/bioproject

Funders

Academy of Finland

Biocodex Microbiota Foundation

Dupont Nutrition and Health

Dutch Research Council (Nederlandse Organisatie voor Wetenschappelijk Onderzoek, NWO)

European Union Horizon 2020 Research and Innovation Program

Ongoing?
Yes

Data types collected

mentalHealthData
dataLinkage
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Self-report questionnaire – online
Qualitative data collection
  • None
Neuroimaging data collection
  • None
Linked or secondary data
  • Healthcare data
  • Medical birth registry
Features

Engagement

  • Community engagement
  • Keywords

    Biological samples/biospecimens
    Cognition
    Diet and nutrition
    Environmental exposures
    Gastrointestinal system
    Genotyping
    Gut health
    Health and wellbeing
    Human development
    Infant health
    Lifestyle
    Living conditions
    Maternal health
    Paternal health
    Stress
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