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Hepatitis C Virus Research UK Clinical Database and Biobank
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Sample details

The Hepatitis C Virus (HCV) Research UK Clinical Database and Biobank was established by HCV Research United Kingdom (UK), a consortium of leading stakeholders in the UK, including all the major adult and paediatric liver centres. The remit of HCV Research UK is to address critical gaps in our understanding of HCV. The clinical database and biobank included more than 10,000 patients from 3 UK countries (England, Scotland, and Wales) as of July 2015 who had attended a specialist HCV clinic for care/management of their HCV infection. The mean age at baseline was 48.5 years. Although most (58%) participants were aged 45-64 years, the cohort also included 85 children aged under 16 years. In total, 10,184 patients with past or current chronic infection were enrolled into the cohort through attendance at one of 56 specialist UK HCV clinics between March 2012 and July 2015. Almost all of the most populous parts of the UK are represented in the cohort, with most participants recruited from Yorkshire, London, the West Midlands, and Glasgow.

Study design
Biobank, Cohort - clinical, Cohort

Number of participants at first data collection

10,184 (participants)

Recruitment is ongoing

Age at first data collection

Varied (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Patients and clinical populations
Dataset details
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Countries

England, Scotland, United Kingdom of Great Britain and Northern Ireland, Wales

Year of first data collection

2012

Primary Institutions

University of Birmingham (Academic, United Kingdom)

University of Glasgow (Oilthigh Ghlaschu) (Academic, United Kingdom)

University of Nottingham (Academic, United Kingdom)

Links

hcvresearch.uk/

gla.ac.uk/research/az/cvr/research/clinicalresearch/hepc-ssh/hcvuk/

directory.biobankinguk.org/Profile/Biobank/GBR-1-18

Profile paper DOI

doi.org/10.1093/ije/dyw362

Funders

Medical Research Foundation (Third Sector, United Kingdom)

Ongoing?
Yes

Data types collected

mentalHealthData
dataLinkage
Quantitative data collection
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
Qualitative data collection
  • None
Neuroimaging data collection
  • None
Linked or secondary data
  • Healthcare data
  • Mortality data
Features

Engagement

  • Community engagement
  • Keywords

    Biological samples/biospecimens
    Chronic illness
    Disease progression
    Health behaviour
    Hepatitis
    Lifestyle factors
    Physical health
    Risk factors
    Treatment experiences and outcomes
    Viruses
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