High-Risk Study of Bipolar Disorder
The High-Risk Study of Bipolar Disorder is a longitudinal, prospective investigation of individuals at risk for bipolar disorder (BP) and related disorders. The cohort consists of adolescents aged 12 to 21 years, with (n = 141) and without (n = 91) family members (probands) with a diagnosis of BP and related disorders. Probands' diagnoses represent a lifetime DSM-IV diagnosis of either BPI (n = 126 adolescents related to 78 probands), BPII with recurrent major depression (n = 10 adolescents related to 6 probands), or schizoaffective disorder, bipolar type (n = 5 adolescents related to 4 probands). Data was collected between 2006 and 2009.
Study design
Cohort
Number of participants at first data collection
232 (participants)
Age at first data collection
12 to 21 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2006
Primary Institutions
Indiana University School of Medicine (IU School of Medicine)
Johns Hopkins University (JHU)
University of Michigan
Washington University in St. Louis (WashU)
Profile paper DOI
Funders
National Institutes of Health (NIH)
Ongoing?
No
Data types collected
- Interview – face-to-face
- Interview – phone
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- None
- None
- Healthcare data
Engagement
Keywords
