Home Observation of Periconceptional Exposures (HOPE)
The HOPE study aimed to accomplish home-collected, individual-level biomonitoring among heterosexual couples during the sensitive windows of conception, implantation, and very early pregnancy. Between 2011 and 2015, the study enrolled 183 heterosexual couples (women aged 18 to 35 years and men aged 18 to 40 years) who planned to conceive within three months of enrollment, had no known fertility issues, and resided in the Salt Lake City, Utah area in the United States of America. Baseline visits were conducted during approximately the first 10 days of the menstrual cycle, and couples were followed for up to 12 months, including regular online questionnaires and biospecimen collections. Additionally, families from the HOPE study are followed in the Utah Children’s Project (UCP) as part of the Environmental Influences on Child Health Outcomes (ECHO) consortium.
Study design
Cohort
Number of participants at first data collection
183 (female participants)
183 (male participants)
Age at first data collection
18 - 35 years (female participants)
18 - 40 years (male participants)
Participant year of birth
Varied (female participants)
Varied (male participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2011
Primary Institutions
University of Utah
Profile paper DOI
Funders
National Institute of Environmental Health Sciences (NIEHS)
Ongoing?
No
Data types collected
- Activity log (e.g. food, sleep, exercise)
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Secondary data
- Self-report questionnaire – online
- None
- None
- Healthcare data
Engagement
Keywords
Consortia and dataset groups
