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Hortega Study
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Sample details

The Hortega Study is a population-based cohort study designed to investigate both traditional and non-traditional risk factors for cardiometabolic diseases. It comprises approximately 1,500 adult participants from the catchment area of the University Hospital Rio Hortega in Valladolid, Spain. Participants were recruited between 2001 and 2003 through random sampling from the regional health card census, after an initial mailed survey to potential participants and a phase of pilot testing. Participants were followed for over 14 years through passive linkage to electronic health records and mortality registries, with a follow-up conducted in 2015 and plans for future active re-examination of elderly survivors.

Study design
Cohort

Number of participants at first data collection

1,502 (participants)

Age at first data collection

Varied (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Adults
Community-based sample
Older and elderly people
Dataset details

Country

Spain

Year of first data collection

2001

Primary Institutions

Carlos III Health Institute (Instituto de Salud Carlos III)

University Hospital Río Hortega (Hospital Universitario Río Hortega)

University of Valladolid (Universidad de Valladolid)

Links

doi.org/10.1016/j.ejim.2025.03.022

Funders

Carlos III Health Institute (Instituto de Salud Carlos III, ISCIII)

Centro de Investigación Biomédica en Red (CIBER)

European Commission

European Regional Development Fund (ERDF)

European Union FP7 programmes

Ongoing?
Yes

Data types collected

dataLinkage
Quantitative data collection
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
  • Self-report questionnaire – paper or computer assisted
Qualitative data collection
  • None
Neuroimaging data collection
  • None
Linked or secondary data
  • Healthcare data
  • Mortality data
Features

Engagement

  • None
  • Keywords

    Anthropometry
    Biological samples/biospecimens
    Cardiometabolic risk
    Chronic illness
    Clinical outcomes
    Genetics
    Lifecourse
    Metabolomics
    Morbidity and mortality
    Physical health
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