IAVI’s HIV epidemiology and early infection cohort studies
Starting in 2004, IAVI established partnerships with nine experienced clinical research centres in east and southern Africa (in Uganda, Rwanda, Kenya, Zambia, and South Africa) to enrol suitable volunteers to undertake research on human immunodeficiency virus (HIV) epidemiology and vaccines and to better understand at-risk populations. Two cohorts were established that followed persons at risk of HIV acquisition (IAVI Protocol B and the HT study). Between 2005 and 2009, varying by research centre, through to December 2011, these cohorts served as the source populations for a third cohort study on the natural history of HIV infection (IAVI Protocol C).
Study design
Cohort
Number of participants at first data collection
10,375 (participants)
Age at first data collection
Varied (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Countries
Year of first data collection
2005
Primary Institutions
International AIDS Vaccine Initiative (IAVI)
Links
No website available
Profile paper DOI
Funders
Bill & Melinda Gates Foundation
National Institute of Allergy and Infectious Diseases (NIAID)
National Institutes of Health (NIH)
Office of Research Infrastructure Programs (ORIP)
United States Agency for International Development (USAID)
Ongoing?
Yes
Data types collected
- Interview – face-to-face
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Secondary data
- None
- None
- Existing research data
Engagement
Keywords
