Infant Brain Imaging Study (IBIS)

Sample details

IBIS aims to investigate brain and behaviour development in infants at risk for developing autism. Participants were children at low and high familial likelihood for autism spectrum disorder (ASD) that attended an assessment at one of five study centres across the United States of America. Caregivers and an older sibling of the participant were also assessed. Over 400 participants completed baseline assessment beginning in 2010. Participants are followed-up at age 6 months, 12 months, 24 months and at school age (7 to 14 years). IBIS is part of the Environmental Influences on Child Health Outcomes (ECHO) initiative which aims to understand the influence of environmental exposures on the health and development of children. Participants in IBIS can complete optional additional assessments for ECHO.

Study design
Cohort

Number of participants at first data collection

318 (high familial risk for ASD)

117 (low familial risk for ASD)

Recruitment is ongoing

Age at first data collection

6 months (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Autism Spectrum Disorder (ASD)

Children and young people

Healthy

Newborns, infants and babies

School-aged children

Dataset details

Country

United States of America

Year of first data collection

2010

Primary Institutions

Children's Hospital of Philadelphia (CHOP)

University of Minnesota

University of North Carolina at Chapel Hill (UNC)

University of Washington (UW)

Washington University in St. Louis (WashU)

Links

ibis-network.com/

reporter.nih.gov/project-details/10919227

doi.org/10.1016/j.dcn.2023.101333

Profile paper DOI

doi.org/10.1038/nature21369

Funders

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

National Institutes of Health (NIH)

Ongoing?
Yes

Data types collected

Quantitative data collection

Audio or visual recordings (e.g. of child behaviour, facial expressions)
Interview – face-to-face
Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
Self-report questionnaire – online
Self-report questionnaire – unspecified

Qualitative data collection