Incidence of Cognitive Impairment in Cohorts with Longitudinal Evaluation - PD (ICICLE-PD)
The ICICLE-PD study aims to identify patients who develop Parkinson’s disease dementia (PDD) and the factors that predict its evolution. From this information, a simplified panel of tests that can be used to predict PDD will be established. Participants were recruited between June 2009 and March 2012 from clinical sites, advertising and primary health care networks in Newcastle-Gateshead and Cambridgeshire, United Kingdom. Around 250 participants with Parkinson’s Disease (PD) and 100 controls completed baseline assessment and are being followed up every 18 months.
Study design
Cohort, Cohort - clinical
Number of participants at first data collection
259 (PD patients)
99 (controls)
Age at first data collection
≥ 45 years (PD patients)
≥ 45 years (controls)
Participant year of birth
Varied (PD patients)
Varied (controls)
Participant sex
All
Representative sample at baseline?
No
Sample features
Countries
Year of first data collection
2009
Primary Institutions
Newcastle University
University of Cambridge
Links
Profile paper DOI
Funders
Lockhart Parkinson's Disease Research Fund
Michael J. Fox Foundation for Parkinson's Research
National Health Service (NHS)
National Institute for Health and Care Research (NIHR)
Parkinson's UK
Ongoing?
Yes
Data types collected
- Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
- Interview – face-to-face
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- None
- Magnetic Resonance Imaging (MRI)
- Positron Emission Tomography (PET)
- None
Engagement
Keywords
