IIS started in 1996 with the goal of exploring immune system markers of the early life origins of asthma. Over the next 7 years, 482 mothers in the third trimester of pregnancy agreed to enroll their infant in the study at birth. Including the collection of umbilical cord blood, there have been 7 evaluations completed at ages 3 months, and 1, 2, 3, 5, and 9 years of age. The IIS is a population-based, non-selected, prospective birth cohort study. Mothers were recruited during prenatal visits at 5 sites in Tucson, Arizona, United States of America between 1997 and 2003.
Study design
Cohort - primary caregiver and child, Cohort - birth
Number of participants at first data collection
482 (mothers)
482 (children)
Age at first data collection
Varied (mothers)
Birth (children)
Participant year of birth
Varied (mothers)
1997 - 2003 (children)
Participant sex
Female
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
1997
Primary Institutions
University of Arizona College of Medicine – Tucson
Profile paper DOI
Funders
National Institutes of Health (NIH)
Ongoing?
No
Data types collected
Engagement
Keywords
Consortia and dataset groups