IIS started in 1996 with the goal of exploring immune system markers of the early life origins of asthma. Over the next 7 years, 482 mothers in the third trimester of pregnancy agreed to enroll their infant in the study at birth. Including the collection of umbilical cord blood, there have been 7 evaluations completed at ages 3 months, and 1, 2, 3, 5, and 9 years of age. The IIS is a population-based, non-selected, prospective birth cohort study. Mothers were recruited during prenatal visits at 5 sites in Tucson, Arizona, United States of America between 1997 and 2003.
Study design
Cohort - primary caregiver and child, Cohort - birth
Number of participants at first data collection
482 (mothers)
482 (children)
Age at first data collection
Varied (mothers)
Birth (children)
Participant year of birth
Varied (mothers)
1997 - 2003 (children)
Participant sex
Female
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
1997
Primary Institutions
University of Arizona College of Medicine – Tucson (Academic, United States of America)
Profile paper DOI
Funders
National Institutes of Health (NIH) (Government, United States of America)
Ongoing?
No
Data types collected
Engagement
Keywords
Consortia and dataset groups