Imaging in Lifelines (ImaLife)
The ImaLife study, embedded in the Lifelines cohort, is a population-based study in the northern part of the Netherlands in the regions of Drenthe, Friesland, and Groningen. It is designed to establish the reference values of the imaging biomarkers for lung cancer, chronic obstructive pulmonary disease (COPD), and coronary artery disease (CAD) in a sample aged 45 years and older. About 12,000 participants have been recruited for the study. Participants undergo a low dose chest computed tomography (CT) and a coronary artery calcium score (CACS) acquisition, followed by a repeat lung scan after 3 or 4 months to assess the volume doubling time. The ImaLife data can be linked to the Lifelines data.
Study design
Cohort
Number of participants at first data collection
12,094 (participants)
Age at first data collection
≥ 45 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2016 (ImaLife)
2006 (Lifelines linkage)
Primary Institutions
University of Groningen (Rijksuniversiteit Groningen, UG)
Profile paper DOI
Funders
Ministry of Economic Affairs (Ministerie van Economische Zaken, EZ)
Siemens Healthineers
Ongoing?
No
Data types collected
- Secondary data
- None
- Computerized tomography (CT)
- Existing research data
Engagement
Keywords
