Imperial Amyloid PET Cohort (Imperial APC)
The Imperial APC study aims to investigate the diagnostic utility of amyloid Positron Emission Tomography (PET) and other more established biomarkers of Alzheimer's Disease (AD) in a clinical cohort of patients with atypical clinical presentations. In this sub-study, the researchers retrospectively collected MRI scans of all individuals referred for amyloid PET imaging at the Imperial College Healthcare NHS Trust Memory Clinic between 2013 and 2021. Participants were included in the sample if they had received a referral for clinical amyloid PET in line with appropriate use criteria and had an available MRI scan within 12 months of amyloid PET.
Study design
Cohort - clinical, Cohort
Number of participants at first data collection
351 (participants)
Recruitment is ongoing
Age at first data collection
Varied (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Countries
Year of first data collection
2013
Primary Institutions
Imperial College London (Imperial, ICL) (Academic, United Kingdom)
Profile paper DOI
Funders
Alzheimer's Society (Third Sector, United Kingdom)
Ongoing?
No
Data types collected
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Secondary data
- None
- Magnetic Resonance Imaging (MRI)
- Positron Emission Tomography (PET)
- Healthcare data
Engagement
Keywords
