IMPROVE aimed to investigate carotid intima-media thickness and its progression as predictors of vascular events in European individuals at high risk of cardiovascular diseases. Over 3,700 participants were enrolled on the study at centres in Kuopio (Finland, two centres), Stockholm (Sweden), Groningen (the Netherlands), Paris (France), Milano and Perugia (Italy). Participants were aged 55 to 79 and had at least three vascular risk factors. Baseline assessment began in 2004, and participants were followed up 15, 30 and 36 months after baseline.
Study design
Cohort
Number of participants at first data collection
3,703 (participants)
Age at first data collection
55 - 79 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Countries
Year of first data collection
2004
Primary Institutions
Centro Cardiologico Monzino (IRCCS)
University of Milan (Università degli Studi di Milano)
Links
clinicalepi.i-med.ac.at/research/proof-athero/studies/improve/
cordis.europa.eu/project/id/QLG1-CT-2002-00896
web.archive.org/web/20070529195016/http://users.unimi.it/improve/description%20of%20the%20study.htm
Profile paper DOI
Not available
Funders
British Heart Foundation
European Commission
Foundation for Strategic Research (Fondation pour la recherche stratégique, FRS)
Ministry of Health (Ministero della Salute)
Stockholm County Council (now known as Region Stockholm)
Ongoing?
No
Data types collected
Engagement
Keywords