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Infants' Environmental Health Study (ISA)
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Sample details

The ISA study aimed to investigate the potential effects of prenatal exposure to pesticides and manganese on children’s growth and neurodevelopment. Between 2010 and 2011, the study recruited 451 women who were at least 15 years old, less than 33 weeks pregnant, and lived at least 5 km from a banana plantation in Matina County, Costa Rica. The women were assessed one to three times during pregnancy, and approximately seven weeks postpartum. Infant data was collected from medical records at birth, and the women-infant pairs were further assessed at approximately one year and five years postpartum.

Study design
Cohort - primary caregiver and child

Number of participants at first data collection

451 (pregnant women)

380 (infants)

Age at first data collection

≤ 15 years (pregnant women)

Birth (infants)

Participant year of birth

Varied (pregnant women)

Varied (infants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Children and young people
Mother and child dyad
Mothers
Newborns, infants and babies
Pregnant people
Dataset details

Country

Costa Rica

Year of first data collection

2010

Primary Institutions

National University of Costa Rica (Universidad Nacional de Costa Rica)

Links

isa.una.ac.cr/index.php/en/

doi.org/10.1136/thoraxjnl-2021-218068

Funders

Health Canada

International Development Research Centre (IDRC) (Centre de recherches pour le développement international, CRDI)

National Institute of Environmental Health Sciences (NIEHS)

Swedish Research Council for Environment, Agricultural Sciences and Spatial Planning (FORMAS)

Ongoing?
No

Data types collected

mentalHealthData
dataLinkage
Quantitative data collection
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Self-report questionnaire – paper or computer assisted
Qualitative data collection
  • None
Neuroimaging data collection
  • None
Linked or secondary data
  • Geographic, spatial & environmental data
  • Healthcare data
Features

Engagement

  • Community engagement
  • Keywords

    Anthropometry
    Biological samples/biospecimens
    Diet and nutrition
    Exposure - outcome associations
    Human development
    Lifestyle
    Medical history
    Neurodevelopment
    Occupational
    Pesticide use
    Pregnancy
    Prenatal exposures
    Respiratory health and disease
    Sociodemographics
    Socioeconomics

    Consortia and dataset groups

    AGRICOH
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