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Internalising Behaviors in Children Exposed in Utero to Psychotropic Medications
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Sample details

This study examined internalising behaviours in children prenatally exposed to psychotropic medications. A total of 69 new and expectant mothers were recruited in Vancouver, Canada, between 1997 and 1999, including 46 pregnant women diagnosed with depression or anxiety who were treated with psychotropic medications (exposed group), and 23 healthy postpartum women (comparison group). The exposed group was enrolled via the Reproductive Mental Health Program at British Columbia Women’s Hospital, while the comparison group was recruited after delivery from paediatricians’ offices. Participants were assessed at baseline during pregnancy (the exposed group) or shortly after birth (the comparison group). Of the exposed pregnancies, 22 mother–child dyads were followed up, along with 14 dyads from the healthy group. Follow-ups occurred at birth, 3 months, 8 months, and 4–5 years.

Study design
Cohort, Cohort - birth, Cohort - primary caregiver and child, Cohort - clinical

Number of participants at first data collection

69 (mothers)

36 (children)

Age at first data collection

Varied (mothers)

Birth (children)

Participant year of birth

Varied (mothers)

Varied (children)

Participant sex
All

Representative sample at baseline?
No

Sample features

Children
Control participants
Mother and child dyad
Mothers
Newborns, infants and babies
Dataset details

Country

Canada

Year of first data collection

1997

Primary Institutions

University of British Columbia (UBC)

Links

doi.org/10.1007/s00737-012-0288-9

doi.org/10.4088/jcp.v65n0214

Funders

British Columbia Medical Services Foundation

GlaxoSmithKline (GSK)

Ongoing?
No

Data types collected

mentalHealthData
Quantitative data collection
  • Self-report questionnaire – paper or computer assisted
Qualitative data collection
  • None
Neuroimaging data collection
  • None
Linked or secondary data
  • None
Features

Engagement

  • None
  • Keywords

    Behaviour
    Clinical outcomes
    Environmental factors
    Exposure - outcome associations
    Maternal mental health
    Medication
    Mental health
    Mother-child interactions
    Pregnancy outcomes
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