Korean Brain Aging Study for the Early Diagnosis and Prediction of Alzheimer's Disease (KBASE)
The KBASE is a longitudinal cohort study following individuals with a wide range of cognitive statuses (cognitively normal, mild cognitive impairment, and Alzheimer's disease dementia) to discover novel biomarkers for the early detection of Alzheimer's disease. A total of 591 individuals (365 cognitively normal, 139 mild cognitive impairment, and 87 Alzheimer's disease dementia older adults) aged 20 - 90 years old were recruited from 4 sites (2 university hospital and 2 public centres) in Seoul, South Korea and completed baseline assessment in 2014. Participants are followed annually with clinical and neuropsychological assessments, and biannually with full KBASE assessments, including neuroimaging and blood laboratory tests.
Study design
Cohort - clinical
Number of participants at first data collection
591 (participants)
Age at first data collection
20 - 90 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2014
Primary Institutions
Seoul National University (서울대학교, SNU)
Profile paper DOI
Funders
Ministry of Science and Technology
Ongoing?
Yes
Data types collected
- Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
- Interview – face-to-face
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Secondary data
- Self-report questionnaire – unspecified
- Wearable devices
- None
- Magnetic Resonance Angiography (MRA)
- Arterial Spin Labelling (ASL)
- Functional magnetic resonance imaging (fMRI)
- Magnetic Resonance Imaging (MRI)
- Positron Emission Tomography (PET)
- Healthcare data
Engagement
Keywords
Consortia and dataset groups
