Kuopio Ischaemic Heart Disease Risk Factor Study (KIHD study)
The KIHD study aims to investigate risk factors for cardiovascular, metabolic, and other non-communicable diseases in eastern Finland, an area with a high occurrence of cardiovascular disease. The baseline examinations were carried out from 1984 to 1989 and included over 2,600 randomly chosen middle-aged men, specifically, 42, 48, 54, and 60 years of age. Three more examinations were conducted 4, 11, and 20 years after the baseline examinations and the last two of them also involved 920 postmenopausal women aged 53 to 73 years. Participants have been followed up through linked mortality and healthcare data and the study is ongoing as of 2025.
Study design
Cohort
Number of participants at first data collection
1,166 (first cohort)
1,516 (second cohort)
920 (postmenopausal women)
Age at first data collection
54 years (first cohort)
42 - 60 years (second cohort)
53 - 73 years (postmenopausal women)
Participant year of birth
Varied (first cohort)
Varied (second cohort)
Varied (postmenopausal women)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
1984 (first cohort)
1986 (second cohort)
1998 (postmenopausal women)
Primary Institutions
University of Eastern Finland
University of Kuopio (now known as University of Eastern Finland, Itä-Suomen yliopisto)
Links
clinicaltrials.gov/study/NCT03221127
doi.org/10.1001/archinte.160.8.1160
uefconnect.uef.fi/en/kuopio-ischaemic-heart-disease-risk-factor-kihd-study-nutrition/
Profile paper DOI
Not available
Funders
Academy of Finland
Finnish Cultural Foundation (Suomen Kulttuurirahasto)
Jenny and Antti Wihuri Foundation (Jenny ja Antti Wihurin rahasto)
Juho Vainio Foundation
Ministry of Education and Culture (Opetus- ja kulttuuriministeriö)
Ongoing?
Yes
Data types collected
- Activity log (e.g. food, sleep, exercise)
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Secondary data
- Self-report questionnaire – paper or computer assisted
- None
- None
- Healthcare data
- Mortality data
Engagement
Keywords
Consortia and dataset groups
