Learning and Relapse Risk in Alcohol Dependence (LeAD project 2)
This study investigated the behavioural, neuroimaging, and clinical predictors of relapse in treatment-seeking alcohol-dependent patients. The sample consisted of 114 recently detoxified alcohol-dependent patients (16% female) and 98 matched control participants (17% female) who were recruited from two sites in Germany; Berlin and Dresden. Patients had a diagnosis of alcohol dependence for a minimum of 3 years and had gone through detoxification procedures on average 4 times. After baseline assessment, patients were followed up every 2 weeks for 3 months, then again at 24, 36, and 48 weeks.
Study design
Cohort - clinical
Number of participants at first data collection
114 (alcohol-dependent patients)
Age at first data collection
≥ 18 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2012
Primary Institutions
Charité – Berlin University Medicine (Charité – Universitätsmedizin Berlin)
Technical University of Munich (Technische Universität München, TU Munich)
Profile paper DOI
Funders
German Research Foundation (Deutsche Forschungsgemeinschaft, DFG)
Ongoing?
No
Data types collected
- Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
- Interview – phone
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Self-report questionnaire – paper or computer assisted
- None
- Functional magnetic resonance imaging (fMRI)
- Magnetic Resonance Imaging (MRI)
- Positron Emission Tomography (PET)
- None
Engagement
Keywords
Consortia and dataset groups
