Long Life Family Study (LLFS)
The LLFS examines the genetic and non-genetic determinants of exceptional longevity and healthy ageing. Beginning in 2006, the study includes nearly 5,000 participants from 539 two-generation families in the USA and Denmark. Participants include long-lived individuals aged at least 78 years in the USA and 86 years in Denmark, along with over 1,000 of their siblings, 2,300 offspring, and approximately 750 spousal controls. Follow-up assessments were conducted during a second visit between 2014 and 2017, with a third follow-up ongoing since 2020.
Study design
Cohort - intergenerational
Number of participants at first data collection
4,953 (participants)
Recruitment is ongoing
Age at first data collection
Varied (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Countries
Year of first data collection
2006
Primary Institutions
Boston University (BU) (Academic, United States of America)
Columbia University (Academic, United States of America)
Duke University (Academic, United States of America)
University of Maryland, College Park (UMD) (Academic, United States of America)
University of Minnesota (Academic, United States of America)
Profile paper DOI
Funders
National Institute on Aging (NIA) (Government, United States of America)
National Institutes of Health (NIH) (Government, United States of America)
Ongoing?
Yes
Data types collected
- Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
- Interview – face-to-face
- Interview – phone
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Secondary data
- Self-completed questionnaire – paper or computer assisted
- Voice capture (e.g. timbre, emotional fluctuations)
- None
- None
- Census data
- Healthcare data
- Mortality data
- Other government data
Engagement
Keywords
Consortia and dataset groups
