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Longitudinal Assessment of Neural Circuits in Adolescents with Anorexia Nervosa
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Sample details

This study investigated how the brain changes over time in adolescents with and without anorexia nervosa in the United States of America. Participants were adolescents between the ages of 12 and 18 years who were assigned female sex at birth and had no major medical or neurologic illness. A total of 89 adolescents with anorexia nervosa and 42 healthy controls participated in baseline assessments between 2017 and 2022. Participants were followed up at one and two years after baseline.

Study design
Cohort, Cohort - clinical

Number of participants at first data collection

89 (participants with anorexia nervosa)

42 (healthy controls)

Age at first data collection

12 - 18 years (participants with anorexia nervosa)

12 - 18 years (healthy controls)

Participant year of birth

Varied (participants with anorexia nervosa)

Varied (healthy controls)

Participant sex
Female

Representative sample at baseline?
No

Sample features

Adolescents
Control participants
People with psychiatric conditions
Dataset details

Country

United States of America

Year of first data collection

2017

Primary Institutions

New York State Psychiatric Institute

Links

github.com/Columbia-Center-for-EDs/Longitudinal-Assessment-of-Teens-with-Anorexia-Nervosa

reporter.nih.gov/project-details/9690173

columbiapsychiatry.org/research/research-clinics/eating-disorders-clinic/research-studies

doi.org/10.1111/jcpp.14066

Profile paper DOI

doi.org/10.1038/nn.4136

Funders

National Institute of Mental Health (NIMH)

Ongoing?
No

Data types collected

neuroImagingData
mentalHealthData
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Self-report questionnaire – paper or computer assisted
Qualitative data collection
  • None
Neuroimaging data collection
  • Functional magnetic resonance imaging (fMRI)
  • Magnetic Resonance Imaging (MRI)
Linked or secondary data
  • None
Features

Engagement

  • None
  • Keywords

    Anthropometry
    Anxiety
    Body mass index (BMI)
    Brain connectivity
    Decision making
    Demographics
    Depression
    Eating disorders
    Eating habits
    Experimental
    Mental health
    Neurodevelopment
    Neuroimaging
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