Longitudinal Study of Genetic Influences on Cognition (LOGIC)
LOGIC aims to reveal developmental trajectories to adult psychiatric illness and provide an evidence base by which to improve risk stratification, early identification, and intervention efforts in referred youth. As of 2023, the cohort includes over 1,000 youth, aged 6 to 17 years, consecutively referred for neuropsychiatric evaluation at Massachusetts General Hospital (MGH) in Boston, United States of America. Participants have been recruited since 2014 through clinical referrals for comprehensive neuropsychiatric evaluations, providing DNA samples and access to their clinical data. Follow-up assessments are conducted periodically, including measures of executive and intellectual functions, and various psychiatric dimensions.
Study design
Cohort - clinical
Number of participants at first data collection
1,137 (participants, as of 2023)
Recruitment is ongoing
Age at first data collection
Varied (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2014
Primary Institutions
Harvard Medical School (HMS)
Profile paper DOI
Funders
David Judah Foundation
Stanley Medical Research Institute (SMRI)
Ongoing?
Yes
Data types collected
- Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
- Interview – face-to-face
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Secondary data
- Self-report questionnaire – paper or computer assisted
- None
- None
- Healthcare data
Engagement
Keywords
