Chongqing Longitudinal Twin Study (LoTiS)
The LoTiS cohort study recruited women pregnant with twins aged 20 to 40 years from multiple antenatal clinics at the two major public hospitals in Chongqing, China, namely the First Affiliated Hospital of Chongqing Medical University and the Chongqing Health Centre for Women and Children, between January 2016 and September 2018. The women were followed up in early, middle, and late pregnancy, then again at delivery, and their offspring were followed up at birth, 6 weeks, then 3, 6, 12, 18, 24, 30, and 36 months of age. The average age of mothers at first follow-up was 29.48 years, 41.7% pregnancies were monochorionic, and the remaining were dichorionic.
Study design
Cohort - birth
Number of participants at first data collection
439 (pregnant women)
333 (twin pregnancies)
Age at first data collection
20 - 40 years (mothers)
Birth (twins)
Participant year of birth
Varied (mothers)
2016 (twins)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2016
Primary Institutions
Chongqing Medical University (重庆医科大学, CQMU)
Profile paper DOI
Funders
Chongqing Municipal Education Commission
Ministry of Science and Technology (中华人民共和国科学技术部)
National Key Research and Development Program of China (NKRDP, 国家重点研发计划)
National Natural Science Foundation of China (国家自然科学基金委员会, NSFC)
Ongoing?
Yes
Data types collected
- Interview – face-to-face
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- None
- None
- Healthcare data
Engagement
Keywords
Consortia and dataset groups
