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Longitudinal Study of Cognitive Change in Normal Healthy Old Age (LSCC)
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Sample details

This study followed the cognitive changes in a sample of 6,542 healthy residents from Greater Manchester and Newcastle-Upon-Tyne, England, who were aged 42-92 years at recruitment. Participant recruitment began in 1983, and new participants were recruited at each wave until 1992. Surviving participants were assessed every two years until 2003.

Study design
Cohort

Number of participants at first data collection

2,052 (Newcastle participants)

2,193 (Manchester participants)

Age at first data collection

42 - 92 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Adults
Older and elderly people
Dataset details
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Countries

England, United Kingdom of Great Britain and Northern Ireland

Year of first data collection

1983

Primary Institutions

University of Manchester

Links

neurodegenerationresearch.eu/cohort/longitudinal-study-of-cognitive-change-in-normal-healthy-old-age/

Funders

Economic and Social Research Council (ESRC)

Medical Research Council (MRC)

UK Social Science Research Council

Unilever PLC

Wellcome Trust

Ongoing?
No

Data types collected

neuroImagingData
mentalHealthData
dataLinkage
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Self-report questionnaire – paper or computer assisted
Qualitative data collection
  • None
Neuroimaging data collection
  • Magnetic Resonance Imaging (MRI)
Linked or secondary data
  • Census data
  • Mortality data
Features

Engagement

  • None
  • Keywords

    Ageing
    Alzheimer's disease (AD)
    Biological samples/biospecimens
    Cognitive ageing and decline
    Depression
    Lifestyle
    Mild cognitive impairment (MCI)
    Neuroimaging
    Socioeconomics
    Stressful life events
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