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Life Span Study (LSS)
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Sample details

Cohorts of atomic bomb survivors, including those exposed in utero and children conceived after parental exposure, were established to investigate the late health effects of atomic bomb radiation in Japan and its transgenerational effects. The LSS (the cohort of survivors) consists of about 120,000 subjects who have been followed since 1950. The cohort consists of residents of Hiroshima and Nagasaki, identified through the national census in 1950, including 94,000 atomic-bomb survivors and 27,000 unexposed individuals.

Study design
Cohort

Number of participants at first data collection

120,321 (participants)

Age at first data collection

Varied (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
The general population of Hiroshima and Nagasaki, Japan.

Sample features

Adults
Children and young people
Intergenerational
Parents
Population-based sample
Dataset details

Country

Japan

Year of first data collection

1950

Primary Institutions

Radiation Effects Research Foundation (放射線影響研究所, RERF)

Links

rerf.or.jp/en/programs/research_activities_e/outline_e/proglss-en/

Funders

Department of Energy (DOE)

Ministry of Health, Labor and Welfare (厚生労働省, MHLW)

National Academy of Sciences (NAS)

Ongoing?
Yes

Data types collected

dataLinkage
Quantitative data collection
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
Qualitative data collection
  • None
Neuroimaging data collection
  • None
Linked or secondary data
  • Healthcare data
  • Mortality data
Features

Engagement

  • None
  • Keywords

    Biological samples/biospecimens
    Cancer
    Chemical exposures
    Morbidity and mortality
    Survivors
    Trauma
    War

    Consortia and dataset groups

    Asia Cohort Consortium (ACC)
    Radiation Effects Research Foundation (RERF)
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