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Microbes, Allergy, Asthma, and Pets birth cohort (MAAP)
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Sample details

The Microbes, Asthma, Allergy and Pets (MAAP) birth cohort is designed to study the effects of indoor dog exposure on early-life gut microbiome development and the risk of asthma and allergies in children. Pregnant women aged 18-49, receiving healthcare from Henry Ford Health System, were recruited if they lived with indoor dogs or in pet-free households for at least 2 years before pregnancy. MAAP includes 141 maternal–child pairs from southeastern Michigan in the United States of America. Participants were followed up at four time points: prenatal, 1-week post-delivery, 6 months post-delivery, and 18 months post-delivery.

Study design
Cohort - primary caregiver and child

Number of participants at first data collection

141 (mothers)

141 (children)

Age at first data collection

Varied (mothers)

Birth (children)

Participant year of birth

Varied (mothers)

2014 - 2016 (children)

Participant sex
All

Representative sample at baseline?
No

Sample features

Children and young people
Mother and child dyad
Dataset details

Country

United States of America

Year of first data collection

2014 (participants)

Primary Institutions

Henry Ford Health

University of California, San Francisco (UCSF)

Links

doi.org/10.1186/s12931-019-1088-9

Profile paper DOI

doi.org/10.1111/cea.14303

Funders

Henry Ford Health

National Institute of Allergy and Infectious Diseases (NIAID)

National Institutes of Health (NIH)

Ongoing?
No

Data types collected

dataLinkage
Quantitative data collection
  • Activity log (e.g. food, sleep, exercise)
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
  • Self-report questionnaire – paper or computer assisted
Qualitative data collection
  • None
Neuroimaging data collection
  • None
Linked or secondary data
  • Healthcare data
Features

Engagement

  • None
  • Keywords

    Allergies
    Asthma
    Biological samples/biospecimens
    Biomarkers
    Disease transmission
    Genetics
    Gut health
    Infant biosamples
    Microbiome
    Physical health
    Prenatal exposures
    Women's health

    Consortia and dataset groups

    Children’s Respiratory and Environmental Workgroup (CREW)
    Environmental influences on Child Health Outcomes (ECHO)
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