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Manchester Asthma and Allergy Study (MAAS)
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Sample details

MAAS investigated the development of asthma and allergic disease in a cohort of parents and children in the United Kingdom. Participants were over 3,600 mothers and 2,000 fathers recruited during antenatal appointments from 1995 to 1997. Over 1,000 of their children who were born at Wythenshawe Hospital, Manchester and Stepping Hill Hospital, Stockport, were also included in the study. Parents completed skin prick tests and questionnaires at baseline, and children were assessed at birth, 1, 3, 5, 8 and 11 years old.

Study design
Cohort, Cohort - birth, Cohort - primary caregiver and child

Number of participants at first data collection

3,618 (mothers)

2,172 (fathers)

1,085 (children)

Age at first data collection

18 - 45 years (mothers)

18 - 45 years (fathers)

Birth (children)

Participant year of birth

Varied (mothers)

Varied (fathers)

1996 - 1998 (children)

Participant sex
All

Representative sample at baseline?
No

Sample features

Fathers
Mother-father-baby triad
Mothers
Newborns, infants and babies
Dataset details
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Countries

England, United Kingdom of Great Britain and Northern Ireland

Year of first data collection

1995

Primary Institutions

University of Manchester

Wythenshawe Hospital

Links

doi.org/10.1186/ISRCTN72673620

doi.org/10.1016/j.jaci.2015.03.041

doi.org/10.1046/j.1365-2222.2001.01050.x

doi.org/10.1111/cea.13319

Funders

Asthma + Lung UK

Jon Moulton Charity Trust

Medical Research Council (MRC)

North West Lung Centre Charity

Ongoing?
No

Data types collected

dataLinkage
Quantitative data collection
  • Interview – face-to-face
  • Interview – phone
  • Physical environment assessment (e.g. pollution, mould)
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
  • Self-report questionnaire – unspecified
Qualitative data collection
  • None
Neuroimaging data collection
  • None
Linked or secondary data
  • Healthcare data
Features

Engagement

  • Community engagement
  • Keywords

    Allergies
    Asthma
    Biological samples/biospecimens
    Environmental exposures
    Gene-environment interactions (GxE)
    Paediatric development
    Prenatal risk factors
    Respiratory health and disease
    Spirometry

    Consortia and dataset groups

    European Study of Cohorts for Air Pollution Effects (ESCAPE)
    Study Team for Early Life Asthma Research (STELAR) consortium
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