35th Multicenter Airway Research Collaboration (MARC-35)
MARC-35, also known as the WIND Study, aims to examine the relationship between bronchiolitis, airway microbiome and subsequent development of recurrent wheezing or asthma later in life. Participants are around 1,000 infants hospitalised due to bronchiolitis at one of 17 sites across the United States of America. Baseline data was collected at enrolment from 2011 to 2014, and participants are being followed up every six months, including more detailed follow-ups at three, six and nine years of age.
Study design
Cohort, Cohort - clinical
Number of participants at first data collection
1,016 (participants)
Age at first data collection
< 1 year (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2011
Primary Institutions
Emergency Medicine Network (EMNet)
Links
emnet-usa.org/research/studies/marc-35/
doi.org/10.1016/j.annepidem.2020.10.001
Profile paper DOI
Funders
National Institutes of Health (NIH)
Ongoing?
Yes
Data types collected
Quantitative data collection
- Interview – face-to-face
- Interview – phone
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Secondary data
Qualitative data collection
- None
Neuroimaging data collection
- None
Linked or secondary data
- Healthcare data
Engagement
Keywords
Consortia and dataset groups
