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Maternal Lifestyle Study (MLS)
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Sample details

MLS was a longitudinal multi-site observational study of the long-term effects of in-utero exposure to cocaine on child development. MLS was conducted at four geographically diverse sites across the United States of America. Participants were identified during the newborn period while in the hospital and consisted of around 1,400 infant-mother dyads. Baseline assessment occurred from 1993 to 1995 and there were follow-ups of caregivers, children and the environment from one month to 16 years after baseline.

Study design
Cohort - primary caregiver and child, Cohort - birth

Number of participants at first data collection

1,388 (mother-child dyads)

Age at first data collection

Varied (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Mother and child dyad
Mothers
Newborns, infants and babies
Substance users
Dataset details

Country

United States of America

Year of first data collection

1993

Primary Institutions

National Institute of Child Health and Human Development (NICHD)

Links

icpsr.umich.edu/web/NAHDAP/studies/34312

doi.org/10.1542/peds.107.2.309

Funders

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

National Institute of Mental Health (NIMH)

National Institute on Drug Abuse (NIDA)

National Institutes of Health (NIH)

United States Department of Health and Human Services

Ongoing?
No

Data types collected

mentalHealthData
dataLinkage
Quantitative data collection
  • Audio or visual recordings (e.g. of child behaviour, facial expressions)
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
  • Self-report questionnaire – paper or computer assisted
  • Wearable devices
Qualitative data collection
  • None
Neuroimaging data collection
  • None
Linked or secondary data
  • Census data
  • Geographic, spatial & environmental data
  • Healthcare data
Features

Engagement

  • None
  • Keywords

    Alcohol use
    Biological samples/biospecimens
    Drug testing
    Human development
    Infant biosamples
    Intrauterine exposures
    Maternal health
    Mental health
    Pregnancy
    Respiratory health and disease
    Risk factors
    Smoking
    Social behaviour
    Social conditions and environment
    Substance use
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