Mood and Brain Circuitry in Adolescents (MBA)
The MBA project aims to investigate neurobehavioral (neural, cognitive, affective, sleep, clinical symptoms) factors that predict levels of manic symptoms during depression (i.e., mixed features) in adolescents varying in levels of depression in the United States of America. The study began in 2017 and has since recruited 181 participants (143 individuals with depression and 38 healthy controls). Participants are assessed at baseline and followed up biannually over a period of 2 to 2.5 years.
Study design
Cohort, Cohort - clinical
Number of participants at first data collection
143 (participants with depression)
38 (healthy controls)
Recruitment is ongoing
Age at first data collection
12 - 18 years (participants with depression)
12 - 18 years (healthy controls)
Participant year of birth
Varied (participants with depression)
Varied (healthy controls)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2017
Primary Institutions
University of Pittsburgh
Profile paper DOI
Funders
National Institute of Mental Health (NIMH)
Ongoing?
Yes
Data types collected
- Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
- Interview – face-to-face
- Self-report questionnaire – paper or computer assisted
- None
- Diffusion Tensor Imaging (DTI)
- Functional magnetic resonance imaging (fMRI)
- None
Engagement
Keywords
