Mayo Clinic Study of Aging (MCSA)
The MCSA has enrolled residents of Olmsted County, Minnesota (United States), without a previous diagnosis of dementia in their medical record. They are evaluated about every 15 to 30 months to determine if they have developed a new onset of mild cognitive impairment or dementia. The sample consisted of randomly selected Olmsted County, Minnesota, residents aged between 70 and 89 years on October 1, 2004. All participants had visited the Mayo Clinic or Olmsted Medical Center at least once within the 3 years prior to the index date. Overall, 52.7% of the subjects were between 70 and 79 years old, 49.0% had more than 12 years of education, and 58.5% were married. The majority were Caucasian (92.9%); 94.1% of in-person participants were retired.
Study design
Cohort
Number of participants at first data collection
2,719 (participants)
Age at first data collection
70 - 89 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2004
Primary Institutions
Mayo Clinic
Profile paper DOI
Funders
National Institute of Mental Health (NIMH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute on Aging (NIA)
Robert H. and Clarice Smith and Abigail Van Buren Alzheimer's Disease Research Program
Ongoing?
Yes
Data types collected
- Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
- Interview – face-to-face
- Interview – phone
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- None
- Magnetic Resonance Imaging (MRI)
- Positron Emission Tomography (PET)
- Healthcare data
Engagement
Keywords
Consortia and dataset groups
