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Metropolit 1953 Danish Male Birth Cohort (Metropolit cohort)
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Sample details

The Metropolit cohort initially aimed to investigate the life course of men to explore intergenerational mobility. In 1965, the study recruited over 11,500 boys born in 1953 in the Copenhagen Metropolitan area (Denmark). Data was collected on participants in 1965, 1966, and 1968. In 2001, the study was revived with a new aim to study the development of chronic disease, including conditions such as Alzheimer's disease, Dementia, Parkinson's disease, and Vascular Dementia. Participants were followed up once more in 2004, and in 2009, eligible members of the Metropolit cohort participated in the Copenhagen Ageing Midlife Biobank (CAMB) study. Approximately 500 participants underwent further neurocognitive testing in 2011. Retrospective data from 1953 and 1971 were collected through birth and healthcare registries. Through national registers, participants were followed up until 2016.

Study design
Cohort - birth, Cohort

Number of participants at first data collection

11,532 (participants)

Age at first data collection

11 - 12 years (participants)

Participant year of birth

1953 (participants)

Participant sex
Male

Representative sample at baseline?
No

Sample features

Children and young people
Dataset details

Country

Denmark

Year of first data collection

1965

1953 (Administrative data)

Primary Institutions

Frederiksberg Hospital

University of Copenhagen (Københavns Universitet, KU)

Links

frederiksberghospital.dk/ckff/sektioner/sbf/psykiatriskepidemiologi/sider/the-danish-metropolit-cohort.aspx

neurodegenerationresearch.eu/cohort/the-metropolit-1953-danish-male-birth-cohort/

Profile paper DOI

doi.org/10.1093/ije/dyi300

Funders

Danish Health Insurance Foundation

Danish Heart Foundation

Else og Mogens Wedell Wedellsborgs Fond

Lundbeck Foundation

Velux Foundation

Ongoing?
No

Data types collected

neuroImagingData
mentalHealthData
dataLinkage
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
  • Self-report questionnaire – paper or computer assisted
Qualitative data collection
  • None
Neuroimaging data collection
  • Electroencephalography (EEG)
  • Functional magnetic resonance imaging (fMRI)
  • Magnetic Resonance Imaging (MRI)
Linked or secondary data
  • Existing research data
  • Healthcare data
  • Medical birth registry
  • Mortality data
  • Other government data
  • Tax, income & benefit data
Features

Engagement

  • None
  • Keywords

    Ageing
    Alzheimer's disease (AD)
    Biological samples/biospecimens
    Dementia
    Health and wellbeing
    Lifecourse
    Lifestyle factors
    Parkinson's disease (PD)
    Social mobility
    Sub-studies
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