The Mano a Mano Cohort is a population-based open cohort study investigating the health of Mexican Americans in the Houston metropolitan area of Texas, USA. Cohort participants are individuals of self-reported Mexican descent who have resided in the metropolitan Houston area for at least 1 year. Participant recruitment began in 2001, and was open to participants of any age; however, since 2014, recruitment is restricted to participants aged 35 to 75 years. As of 2024, the cohort includes around 26,600 adult participants from over 18,000 households. Around 70% of the cohort were born in Mexico, and 77% of the cohort is female. Participants are followed-up annually for up to 20 years.
Study design
Cohort - open
Number of participants at first data collection
26,672 (participants as of 2024)
Recruitment is ongoing
Age at first data collection
≥18 years (adult participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2001
Primary Institutions
University of Texas MD Anderson Cancer Center (Healthcare/Medical, United States of America)
Profile paper DOI
Funders
Caroline W. Law Fund for Cancer Prevention (Third Sector, United States of America)
Duncan Family Institute for Risk Assessment and Cancer Prevention (Research, United States of America)
Texas Tobacco Settlement of 1998 (Industry, United States of America)
Ongoing?
Yes
Data types collected

Engagement
Keywords