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Microisolates in South Tyrol Study (MICROS)
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Sample details

The MICROS study was a longitudinal genetic epidemiology study designed to investigate the genetic structure and epidemiology of complex traits in isolated populations. 1,314 adult residents (aged 18 and older) were enrolled from three isolated municipalities—Stelvio, Martello, and Vallelunga—in the Vinschgau/Val Venosta district of South Tyrol, Italy, between 2002 and 2003, and in 2007. Participants were recruited through community engagement efforts, including public meetings and local advertisements. Follow-up assessments were conducted as needed, depending on the emergence of specific traits, rather than at fixed intervals. The MICROS study has since concluded, and a subset of its participants were later enrolled in the Cooperative Health Research in South Tyrol (CHRIS) study, a larger and ongoing population-based cohort in the same region.

Study design
Cohort

Number of participants at first data collection

1,314 (participants)

Age at first data collection

≥ 18 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Adults
Community-based sample
Dataset details

Country

Italy

Year of first data collection

2002

Primary Institutions

Eurac Research Institute for Biomedicine

Links

doi.org/10.1093/ije/dyaf064

Funders

Ministry of Health of the Autonomous Province of Bolzano

South Tyrolean Sparkasse Foundation

Ongoing?
No

Data types collected

dataLinkage
Quantitative data collection
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
Qualitative data collection
  • None
Neuroimaging data collection
  • None
Linked or secondary data
  • Religious organisation data
Features

Engagement

  • Participant or community advisory groups
  • Community engagement
  • Keywords

    Anthropometry
    Biological samples/biospecimens
    Blood pressure
    Cardiovascular health and disease
    Electrocardiograms
    Epidemiology
    Genetics
    Genomics
    Lifestyle factors
    Neurological examination
    Physical health assessments
    Respiratory health and disease
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