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Minority Aging Research Study (MARS)
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Sample details

MARS studies ageing and risk factors for cognitive decline in minority ethnic groups in the United States of America. The study recruits participants who self identify as African American, are aged at least 65 years and have no diagnosis of dementia or Alzheimer's disease from Chicago, Illinois and its surrounding area. In 2004, 80 participants enrolled in the study. As of 2024, the study includes over 800 participants. As part of the study, participants are given the option to consent to brain donation after death, resulting in 73 autopsies of donated brains as of 2024.

Study design
Cohort, Cohort - open

Number of participants at first data collection

845 (participants as of 2024)

Recruitment is ongoing

Age at first data collection

≥ 65 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

African-American populations
Older and elderly people
Dataset details

Country

United States of America

Year of first data collection

2004

Primary Institutions

Rush University Medical Center (Rush)

Links

rushu.rush.edu/research-rush-university/departmental-research/rush-alzheimers-disease-center/rush-alzheimers-disease-center-research/epidemiologic-research/minority-aging-research-study

maelstrom-research.org/study/mars

dss.niagads.org/cohorts/minority-aging-research-study-mars/

Funders

Illinois Department of Public Health

National Institute on Aging (NIA)

Ongoing?
Yes

Data types collected

neuroImagingData
mentalHealthData
dataLinkage
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
  • Passive electronic data collection (e.g. screen time, scroll speed)
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
  • Self-report questionnaire – paper or computer assisted
  • Wearable devices
Qualitative data collection
  • None
Neuroimaging data collection
  • Magnetic Resonance Imaging (MRI)
Linked or secondary data
  • Existing research data
  • Healthcare data
Features

Engagement

  • Community engagement
  • Participant or community advisory groups
  • Keywords

    Ageing
    Alzheimer's disease (AD)
    Autopsy
    Cognitive ageing and decline
    Decision making
    Dementia
    Lifestyle factors
    Mild cognitive impairment (MCI)
    Organ donation and transplants
    Parkinson's disease (PD)
    Racial minorities
    Stroke
    Sub-studies
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