Mobile High-Resolution Microendoscopy (mHRME) for the Detection of Cervical Dysplasia in El Salvador
This study is a prospective cohort study and aimed to evaluate the performance of the mobile High-Resolution Microendoscopy (mHRME) in a study of 3,000 women in San Salvador, the capital of El Salvador, to assess whether mHRME imaging improves specificity of screening by visual inspection with acetic acid (VIA) or human papillomavirus (HPV) DNA assays without reducing sensitivity for cervical precancer and cancer. Patients were first enrolled at the screening clinic of the Instituto del Cáncer de El Salvador (El Salvador Cancer Institute, ICES), where cervical samples and images of the cervix were taken to conduct a VIA or HPV test. For their second visit, women with a positive VIA or HPV test underwent additional evaluation: urine pregnancy test, VIA, colposcopy, Lugol's solution application, and a HRME.
Study design
Cohort
Number of participants at first data collection
3,000 (participants)
Age at first data collection
30 - 49 years (participants)
Participant year of birth
Varied (participants)
Participant sex
Female
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2015
Primary Institutions
William Marsh Rice University
Links
Profile paper DOI
Funders
National Institutes of Health (NIH)
Ongoing?
No
Data types collected
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- None
- None
- None
Engagement
Keywords
