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Moli-Sani Study
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Sample details

The Moli-Sani study aims to evaluate the risk factors (environmental, genetics, and biomolecular) linked to chronic-degenerative disease. The sample consists of close to 25,000 participants aged 35 to 98 recruited between 2005 and 2010 from the Molise region in Italy. Data collection includes ongoing assessments and recalls, with baseline and follow-up assessments covering a wide range of clinical, biological, and psychometric measures, including imaging for a subsample of around 3,000 participants.

Study design
Cohort

Number of participants at first data collection

24,325 (participants)

Age at first data collection

35 - 98 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Middle-aged people
Older and elderly people
Dataset details

Country

Italy

Year of first data collection

2005

Primary Institutions

Catholic University of Rome

Istituto Superiore di Sanità (ISS)

Links

moli-sani.org/

classic.clinicaltrials.gov/ct2/show/NCT03242109

doi.org/10.1093/eurheartj/ehab783

Funders

Pfizer Foundation

Italian Ministry of University and Research

Ongoing?
Yes

Data types collected

neuroImagingData
mentalHealthData
dataLinkage
Quantitative data collection
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
Qualitative data collection
  • None
Neuroimaging data collection
  • Magnetic Resonance Imaging (MRI)
Linked or secondary data
  • Healthcare data
Features

Engagement

  • Community engagement
  • Keywords

    Anthropometry
    Diet and nutrition
    Health and wellbeing
    Neurodegeneration
    Neuroimaging
    Physical health
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