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Mild Stroke Study II (MSS-II)
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Sample details

MSS-II aimed to explore the influence of dietary salt intake and hypertension, together with plasma sodium concentration, in cerebral small vessel disease (SVD). In all, 264 patients with non-disabling cortical or lacunar strokes were included. Patients were questioned about their salt intake and plasma sodium concentration was measured. Participants returned approximately 1 to 3 months post-stroke and had a follow-up at 1 year for dynamic contrast-enhanced MRI (DCE-MRI).

Study design
Cohort - clinical

Number of participants at first data collection

264 (participants)

Age at first data collection

≥ 18 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Patients and clinical populations
Stroke patients
Dataset details
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Countries

England, United Kingdom of Great Britain and Northern Ireland

Year of first data collection

No information

Primary Institutions

University of Edinburgh (University o Edinburgh, Oilthigh Dhùn Èideann)

University of Sheffield

Links

cheba.unsw.edu.au/consortia/strokog/studies/mild-stroke-study-ii-MSS-ii

doi.org/10.1016%2Fj.neuroimage.2015.10.018

Funders

Age UK

Chief Scientist Office of Scotland

NHS Lothian Research and Development Office

Row Fogo Charitable Trust

Scottish Funding Council (SFC)

Ongoing?
Yes

Data types collected

neuroImagingData
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
Qualitative data collection
  • None
Neuroimaging data collection
  • Diffusion Tensor Imaging (DTI)
  • Magnetic Resonance Imaging (MRI)
Linked or secondary data
  • None
Features

Engagement

  • None
  • Keywords

    Biomarkers
    Cardiovascular health and disease
    Diet and nutrition
    Hypertension
    Neuroimaging
    Neurology and neurological diseases
    Physical health
    Small vessel disease (SVD)
    Stroke

    Consortia and dataset groups

    Stroke and Cognition consortium (STROKOG)
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