Mild Stroke Study II (MSS-II)
MSS-II aimed to explore the influence of dietary salt intake and hypertension, together with plasma sodium concentration, in cerebral small vessel disease (SVD). Over 260 patients with non-disabling cortical or lacunar strokes were recruited between May 2010 and May 2012. Participants were questioned about their salt intake and plasma sodium concentration was measured. Participants returned approximately 1 to 3 months post-stroke and had a follow-up at 1 year for dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). Participants underwent cognitive assessment at one to three months, and one and three years’ post-index stroke, either in person or over the phone.
Study design
Cohort - clinical, Cohort
Number of participants at first data collection
264 (participants)
Age at first data collection
≥ 18 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Countries
Year of first data collection
2010
Primary Institutions
University of Edinburgh (University o Edinburgh, Oilthigh Dhùn Èideann) (Academic, United Kingdom)
University of Sheffield (Academic, United Kingdom)
Links
cheba.unsw.edu.au/consortia/strokog/studies/mild-stroke-study-ii-MSS-ii
doi.org/10.1016%2Fj.neuroimage.2015.10.018
Profile paper DOI
Funders
Age UK (Third Sector, United Kingdom)
Chief Scientist Office of Scotland (Healthcare/Medical, United Kingdom)
NHS Lothian Research and Development Office (Healthcare/Medical, United Kingdom)
Row Fogo Charitable Trust (Third Sector, United Kingdom)
Scottish Funding Council (SFC) (Research council, United Kingdom)
Ongoing?
No
Data types collected
- Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
- Interview – face-to-face
- Interview – phone
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Secondary data
- Self-completed questionnaire – paper or computer assisted
- None
- Diffusion Tensor Imaging (DTI)
- Magnetic Resonance Imaging (MRI)
- Healthcare data
- Mortality data
Engagement
Keywords
Consortia and dataset groups
