Michigan Twin Neurogenetics Study (MTwiNS)
The MTwiNS follows the brain and behaviour development of 708 adolescent twins from low-income neighbourhoods in lower Michigan in the United States of America. MTwiNS participants and their parents (354 families) were initially recruited and assessed when the twins were aged between 6 and 10 years in the Twin Study of Behavioral and Emotional Development in Children (TBED-C), as part of the broader MSU Twin Registry (MSUTR). Families from TBED-C who resided in neighbourhoods with above average levels of poverty were re-recruited into MTwiNS during adolescence and followed-up with neuroimaging, clinical interviews, family interactions, and self-reports from the child and parent.
Study design
Cohort - twin
Number of participants at first data collection
708 (twin individuals)
354 (families)
Age at first data collection
6 - 10 years (twin individuals)
Varied (families)
Participant year of birth
Varied (twin individuals)
Varied (families)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2015 (TBED-C)
Primary Institutions
Michigan State University (MSU)
University of Michigan
Links
sites.lsa.umich.edu/mindlab/research-projects/michigan-twin-neurogenetics-study-mtwins/
Profile paper DOI
Funders
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH Office of the Director
National Alliance for Research on Schizophrenia & Depression (NARSAD) (now known as Brain & Behaviour Research Foundation; BBRF)
National Institute of Mental Health (NIMH)
The Avielle Foundation
Ongoing?
Yes
Data types collected
- Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
- Interview – face-to-face
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Self-report questionnaire – paper or computer assisted
- None
- Diffusion Tensor Imaging (DTI)
- Functional magnetic resonance imaging (fMRI)
- Magnetic Resonance Imaging (MRI)
- Existing research data
Engagement
Keywords
Consortia and dataset groups
